Modulation of olfactory sensitivity and glucose sensing by the feeding state in obese Zucker rats.
The Zucker fa/fa rat has been widely used as an animal model to study obesity, since it recapitulates most of its behavioral and metabolic dysfunctions, such as hyperphagia, hyperglycemia and insulin resistance.Although it is well established that olfaction is under nutritional and hormonal influences, little is known about the impact of metabolic